Alastair Thompson Selected Research

Mitogen-Activated Protein Kinase Kinases (MEKs)

1/2019

The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.

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Alastair Thompson Research Topics

Disease

26	Neoplasms (Cancer) 03/2022 - 12/2006
25	Breast Neoplasms (Breast Cancer) 08/2021 - 01/2008
7	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2022 - 02/2011
4	Neoplasm Metastasis (Metastasis) 08/2021 - 01/2008
3	Melanoma (Melanoma, Malignant) 01/2019 - 05/2013
1	COVID-19 07/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Pathologic Complete Response 01/2021
1	Skin Neoplasms (Skin Cancer) 01/2019
1	Arthralgia (Joint Pain) 01/2018
1	Hypertension (High Blood Pressure) 01/2018
1	Calcinosis 06/2016
1	Breast Carcinoma In Situ 06/2016
1	Ductal Carcinoma 02/2014
1	Wounds and Injuries (Trauma) 02/2014
1	Nevus (Nevi) 05/2013
1	Ovarian Neoplasms (Ovarian Cancer) 01/2012
1	Peptic Ulcer (Peptic Ulcers) 01/2012
1	Glioblastoma (Glioblastoma Multiforme) 02/2010

Drug/Important Bio-Agent (IBA)

5	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2008
4	Letrozole (Femara)FDA LinkGeneric 01/2021 - 10/2010
4	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 07/2010
3	Proteins (Proteins, Gene)FDA Link 10/2020 - 01/2013
2	Phenobarbital (Luminal)FDA Link 03/2022 - 10/2016
2	Indicators and Reagents (Reagents)IBA 03/2022 - 07/2010
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2018
2	Progesterone Receptors (Progesterone Receptor)IBA 01/2022 - 10/2016
2	Estrogens (Estrogen)FDA Link 07/2021 - 01/2021
2	Hormones (Hormone)IBA 01/2021 - 01/2018
2	Cadherins (E-Cadherin)IBA 01/2018 - 11/2012
2	Aromatase InhibitorsIBA 01/2018 - 10/2010
2	matrigelIBA 01/2018 - 11/2012
2	Pharmaceutical PreparationsIBA 01/2012 - 01/2008
2	Tumor Biomarkers (Tumor Markers)IBA 01/2012 - 04/2008
2	Tamoxifen FDA LinkGeneric 02/2011 - 10/2010
1	ParaffinIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	AnthracyclinesIBA 01/2021
1	taxaneIBA 01/2021
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2021
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021
1	Metformin (Glucophage)FDA LinkGeneric 01/2021
1	Ado-Trastuzumab EmtansineIBA 03/2020
1	pertuzumabIBA 03/2020
1	Trastuzumab (Herceptin)FDA Link 03/2020
1	neratinibIBA 03/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Opioid Analgesics (Opioids)IBA 06/2019
1	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2019
1	2-oxoglutarate 3-dioxygenase prolineIBA 01/2019
1	PD 123319IBA 01/2019
1	CollagenIBA 01/2019
1	Losartan (Cozaar)FDA LinkGeneric 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019
1	Small Interfering RNA (siRNA)IBA 01/2019
1	EMA400IBA 01/2019
1	Mitogen-Activated Protein KinasesIBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2017
1	PlasminogenIBA 01/2017
1	Matrix Metalloproteinases (MMPs)IBA 01/2017
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2017
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2017
1	2- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA 10/2016
1	Estrogen ReceptorsIBA 10/2016
1	Anastrozole (Arimidex)FDA LinkGeneric 10/2016
1	human ERBB2 proteinIBA 10/2016
1	fibrillarinIBA 09/2013
1	tissue-factor-pathway inhibitor 2 (PP5)IBA 05/2013
1	Estrogen Receptor betaIBA 11/2012
1	Spironolactone (Aldactone)FDA LinkGeneric 07/2012
1	PlatinumIBA 01/2012
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2012
1	Phosphotransferases (Kinase)IBA 01/2012
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 07/2010
1	DNA Polymerase thetaIBA 07/2010
1	Cyclin EIBA 07/2010
1	pervanadateIBA 02/2010
1	WortmanninIBA 02/2010

Therapy/Procedure

14	Therapeutics 07/2021 - 01/2008
7	Radiotherapy 11/2021 - 12/2006
6	Neoadjuvant Therapy 08/2021 - 08/2018
5	Segmental Mastectomy (Lumpectomy) 11/2021 - 02/2011
2	Adjuvant Chemotherapy 03/2022 - 08/2021
2	Drug Therapy (Chemotherapy) 10/2018 - 01/2012
2	Mastectomy (Mammectomy) 01/2018 - 06/2016
1	Parathyroidectomy 01/2021
1	Thyroidectomy 01/2021
1	Immunotherapy 01/2020
1	Contraindications 10/2018
1	Operative Surgical Procedures 10/2016
1	Heterologous Transplantation (Xenotransplantation) 11/2012
1	Perioperative Care 01/2012
1	Precision Medicine 01/2012
1	Chemoprevention 01/2008